What dosage strengths are available for Rexulti (brexpiprazole)?

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Last updated: October 27, 2026 • View editorial policy

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Rexulti Dosage Strengths

Rexulti (brexpiprazole) is available in six tablet strengths: 0.25 mg, 0.5 mg, 1 mg, 2 mg, 3 mg, and 4 mg 1.

Tablet Identification

Each strength has distinct visual characteristics for easy identification:

  • 0.25 mg: Light brown, round tablets with "BRX" and "0.25" imprinted
  • 0.5 mg: Light orange, round tablets with "BRX" and "0.5" imprinted
  • 1 mg: Light yellow, round tablets with "BRX" and "1" imprinted
  • 2 mg: Light green, round tablets with "BRX" and "2" imprinted
  • 3 mg: Light purple, round tablets with "BRX" and "3" imprinted
  • 4 mg: White, round tablets with "BRX" and "4" imprinted

All tablets share the same physical characteristics: round, shallow convex, bevel-edged body with markings on one side 1.

Clinical Context

The range of available strengths allows for precise dose titration across Rexulti's approved indications, which include schizophrenia, adjunctive treatment of major depressive disorder, and agitation associated with Alzheimer's disease dementia 1. The lower strengths (0.25 mg and 0.5 mg) are particularly important for initial titration, as the recommended starting dose for agitation in Alzheimer's disease is 0.5 mg daily, with gradual increases to the target dose of 2 mg 1.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.