Vortioxetine Brand Name
The brand name of vortioxetine is Trintellix™ 1.
Important Brand Name History
Vortioxetine was originally marketed under the brand name Brintellix® when it was first approved by the FDA 2, 3, 4, 5, 6. However, due to numerous reports of prescribing and dispensing errors—specifically confusion with the anticoagulant drug Brilinta® (ticagrelor)—the FDA approved a name change 2.
Starting June 1,2016, vortioxetine has been marketed exclusively as Trintellix™ to reduce medication errors 2. While the brand name and National Drug Code (NDC) number changed, the formulation, indication, and dosage information remained identical 2.
Clinical Context
- Generic name: Vortioxetine (or vortioxetine hydrobromide) 1
- Available strengths: 5 mg, 10 mg, and 20 mg tablets 1
- Indication: Treatment of major depressive disorder (MDD) in adults 1, 4, 7
- Mechanism: Multimodal antidepressant with serotonin transporter inhibition and multiple serotonin receptor modulation 1, 3, 6
Common Pitfall to Avoid
Clinicians should be aware that older literature and some international sources may still reference "Brintellix" 3, 4, 5, 6. When prescribing or reviewing medication histories, verify that patients understand both names refer to the same medication to prevent confusion or inadvertent duplication of therapy.