Can vardenafil (Levitra) be taken with Abilify (aripiprazole)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

It is generally safe to take vardenafil (Levitra) with aripiprazole (Abilify), but you should consult your healthcare provider before combining these medications. These two drugs don't have a significant direct interaction that would prevent their combined use. However, both medications can potentially affect your cardiovascular system in different ways. Vardenafil is a phosphodiesterase-5 (PDE5) inhibitor used for erectile dysfunction that can cause blood pressure lowering effects, while aripiprazole is an antipsychotic medication that can occasionally impact heart rhythm. Some patients might experience additive side effects like dizziness or lightheadedness when taking both medications. If you're currently on Abilify and considering starting Levitra, inform your doctor about all medications you're taking, including over-the-counter drugs and supplements. Your doctor may need to adjust dosages or monitor you more closely, especially if you have any underlying cardiovascular conditions, to ensure the combination is safe for your specific health situation.

The safety and efficacy of vardenafil have been established in several studies, including a review of its use in erectile dysfunction 1. Additionally, patient preference studies have compared vardenafil to other PDE5 inhibitors, such as sildenafil and tadalafil, and found that patient preference depends on various factors, including personal characteristics and medication profile 2. A large observational study found that vardenafil, along with other PDE5 inhibitors, was therapeutically effective and improved patient satisfaction in men with erectile dysfunction 3.

When considering the use of vardenafil with aripiprazole, it's essential to weigh the potential benefits and risks, particularly in terms of cardiovascular effects. While there is no significant direct interaction between the two medications, the combination may still pose some risks, especially in patients with underlying cardiovascular conditions. Therefore, it's crucial to consult with a healthcare provider before taking vardenafil with aripiprazole, as they can assess individual patient factors and provide guidance on safe use.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.