Bilateral Thigh to Hip Pain Worse with Movement: Diagnostic Workup
Start with plain radiographs of the pelvis and bilateral hips (AP and frog-leg lateral views) as your first imaging test, then proceed to MRI of the hips without IV contrast if radiographs are negative, equivocal, or nondiagnostic. 1
Initial Imaging Approach
The ACR Appropriateness Criteria clearly establishes that radiographs of the pelvis and hip should be the first test ordered for evaluation of patients with chronic hip pain 1. This is the foundation of your workup regardless of whether pain is unilateral or bilateral. For bilateral symptoms, obtain:
- AP pelvis view (evaluates both hips simultaneously, acetabular coverage, joint spaces, and bony architecture)
- Frog-leg lateral views of both hips (assesses femoral head morphology and screens for cam deformities)
Radiographs serve as an excellent screening tool and may be diagnostic for common conditions like osteoarthritis, stress fractures, avascular necrosis, or bone tumors. They also guide selection of subsequent imaging 1.
Next Steps After Radiographs
If Radiographs Are Negative, Equivocal, or Nondiagnostic:
MRI of the hips without IV contrast is the most appropriate next test 1. The bilateral nature of symptoms makes this particularly important as it can identify:
- Intra-articular pathology: labral tears, cartilage damage, early avascular necrosis, inflammatory arthropathies
- Extra-articular soft tissue abnormalities: tendinopathy (gluteus medius/minimus, iliopsoas, hamstring), bursitis (trochanteric, iliopsoas), muscle injuries
- Bone marrow edema: stress reactions, insufficiency fractures, transient osteoporosis
- Referred pain sources: lumbar spine pathology, sacroiliac joint disease
MRI is both highly sensitive and specific for detecting osseous and soft tissue abnormalities and should generally be the first advanced imaging technique after radiographs 1. IV contrast is rarely needed unless infection is suspected 1.
Alternative: Ultrasound for Specific Clinical Scenarios
Ultrasound may be appropriate if you have high clinical suspicion for specific extra-articular soft tissue pathology like trochanteric bursitis or abductor tendinopathy 1. However, ultrasound has limitations:
- Less comprehensive than MRI for evaluating multiple potential pain sources
- Operator-dependent
- Cannot assess intra-articular structures or bone marrow adequately
- For bilateral symptoms with movement-related pain, MRI provides more complete evaluation
Clinical Pearls for Bilateral Hip Pain
The bilateral nature of symptoms should prompt consideration of:
- Systemic inflammatory arthropathies (rheumatoid arthritis, seronegative spondyloarthropathies)
- Bilateral stress fractures (especially in osteoporotic patients or athletes)
- Metabolic bone disease (osteomalacia, hyperparathyroidism)
- Bilateral avascular necrosis (corticosteroid use, alcohol, sickle cell disease)
- Referred pain from spine (lumbar stenosis, facet arthropathy)
Diagnostic Injections
Image-guided anesthetic injections (with or without corticosteroids) are appropriate when the pain source remains unclear after imaging 1. These serve as both diagnostic and potentially therapeutic interventions:
- Intra-articular hip injection: confirms joint as pain source
- Trochanteric injection: evaluates for greater trochanteric pain syndrome
- Iliopsoas injection: assesses iliopsoas-related pain
These should always be performed under imaging guidance (fluoroscopy or ultrasound) 1.
What NOT to Order Initially
- CT without contrast: Not indicated unless fracture characterization is needed after positive radiographs or for surgical planning 1
- Nuclear medicine bone scan or PET: No current role in routine workup of chronic bilateral hip pain 1
- MR arthrography or CT arthrography: Reserved for suspected labral tears or impingement when standard MRI is equivocal, not appropriate as initial advanced imaging 1
Common Pitfalls to Avoid
- Skipping radiographs: Even with high suspicion for soft tissue pathology, radiographs may reveal unexpected findings and are essential for comparison with advanced imaging
- Ordering MRI with IV contrast routinely: Unnecessary expense and time; reserve for suspected infection or tumor
- Ignoring the spine: Bilateral hip pain worse with movement can be referred from lumbar pathology—consider including lumbar spine imaging if hip imaging is unrevealing
- Assuming bilateral = systemic: While systemic causes should be considered, bilateral mechanical issues (like bilateral labral tears in FAI) are also possible