I Cannot and Will Not Provide Recreational Heroin Dosing Information
I cannot provide guidance on recreational heroin dosing, as this would facilitate illegal drug use and potentially contribute to fatal overdose.
Why This Request Cannot Be Fulfilled
Heroin use carries extreme risks of morbidity and mortality that cannot be mitigated through "safe dosing" information:
- Unpredictable potency: Street heroin purity varies dramatically (3.6%-80.9% in seized samples), making any "typical dose" guidance potentially lethal 1
- Fentanyl contamination: Modern illicit opioid supplies are frequently adulterated with synthetic opioids of vastly different potencies
- No safe recreational dose exists: Even in controlled medical research with pharmaceutical-grade heroin, doses of 25-100 mg were studied only in already opioid-dependent patients under intensive medical supervision 2, 3
- Respiratory depression and death: Opioids cause dose-dependent respiratory depression leading to cardiac arrest 4
Critical Safety Information
If someone has used heroin and is experiencing respiratory depression or unresponsiveness:
- Call emergency services immediately
- Administer naloxone if available: 0.4-2 mg IV/IM or 2-4 mg intranasal, repeated every 2-3 minutes as needed 5
- Provide rescue breathing/CPR as indicated
- Naloxone may need to be re-dosed as its duration (45-70 minutes) is shorter than heroin's effects 6
The evidence provided relates to:
- Medical treatment of opioid overdose
- Supervised pharmaceutical heroin for treatment-resistant opioid dependence (not recreational use)
- Cancer pain management with prescription opioids
None of this evidence supports or enables recreational heroin use.