From the Research
Gastroenterological conditions that can exacerbate rosacea include small intestinal bacterial overgrowth (SIBO), Helicobacter pylori infection, inflammatory bowel disease (IBD), and gastroesophageal reflux disease (GERD), with SIBO and H. pylori infection being the most significant due to their potential for treatment with antibiotics and eradication therapy, respectively, as supported by the most recent study 1.
Key Conditions
- Small intestinal bacterial overgrowth (SIBO)
- Helicobacter pylori infection
- Inflammatory bowel disease (IBD)
- Gastroesophageal reflux disease (GERD)
Mechanisms and Associations
The gut-skin axis plays a crucial role in the relationship between these gastroenterological conditions and rosacea, as intestinal dysbiosis and increased intestinal permeability can lead to systemic inflammation that manifests in the skin 1.
Management and Treatment
Patients with rosacea should consider gastroenterological evaluation if they experience concurrent digestive symptoms or have treatment-resistant skin disease, and treatments such as antibiotics for SIBO and eradication therapy for H. pylori infection may improve skin symptoms in some patients 1.
Quality of Life and Morbidity
Rosacea can significantly affect a patient's emotional health and quality of life, and effective management of gastroenterological conditions may help reduce morbidity and improve quality of life for patients with rosacea 2.