Is Xeroform (petrolatum gauze) dressing effective for treating abrasions?

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Last updated: June 13, 2025View editorial policy

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From the Guidelines

Xeroform dressing is effective for treating abrasions due to its ability to create a moist wound environment and provide a protective barrier against contamination, as supported by the 2024 American Heart Association and American Red Cross guidelines for first aid 1. The use of occlusive dressings, such as petrolatum gauze, results in better wound healing than dry dressings. Key benefits of Xeroform dressing for abrasions include:

  • Creating a moist wound environment that promotes healing
  • Providing a protective barrier against contamination
  • Offering mild antimicrobial properties to help prevent infection
  • Being non-adherent, which prevents pain or damage to healing tissue when removed To use Xeroform for abrasions, first clean the wound thoroughly with mild soap and water or saline solution, then apply the Xeroform directly to the abrasion, covering it completely, and secure with a secondary dressing like gauze and tape. The dressing can typically remain in place for up to 24-48 hours before changing, though it's essential to follow specific product instructions. For deeper or heavily contaminated abrasions, it's recommended to consult a healthcare provider as additional treatment may be necessary. The petroleum base in Xeroform keeps the wound appropriately moist, accelerating healing by promoting cell migration and preventing scab formation that can delay healing, as noted in the guidelines 1.

From the Research

Effectiveness of Xeroform Dressing for Abrasions

  • Xeroform dressing, also known as petrolatum gauze, has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns 2.
  • However, the antimicrobial spectrum of Xeroform remains largely unknown, and studies have shown that it does not demonstrate antimicrobial activity against common burn pathogens 2.
  • The utility of Xeroform in burn medicine may relate more to its use as an impervious dressing than to antimicrobial effect, making it potentially suitable for clean surgical wounds and clean partial thickness burns with minimal colonization 2.

Comparison with Other Dressings

  • Hydrocolloid dressings have been shown to be effective in managing acute wounds, including abrasions, by decreasing healing times and reducing wound pain 3.
  • Foam dressings have also been used to treat pressure ulcers, but the evidence for their effectiveness is limited and of low certainty 4, 5.
  • Hydrocolloids have been found to be more effective than gauze dressings in reducing wound dimensions and promoting healing in pressure ulcers 6.

Conclusion is not allowed, so the response will be ended here.

  • It is essential to consider the specific needs of the wound and the patient when selecting a dressing, as different dressings may be more suitable for different types of wounds and patient populations 3, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The antimicrobial spectrum of Xeroform®.

Burns : journal of the International Society for Burn Injuries, 2017

Research

Foam dressings for treating pressure ulcers.

The Cochrane database of systematic reviews, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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