What is the treatment for tinea versicolor?

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Last updated: June 13, 2025View editorial policy

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From the FDA Drug Label

For treatment of tinea versicolor: Apply to affected areas and lather with a small amount of water. Allow to remain on skin for 10 minutes. Rinse body thoroughly. Repeat this procedure once a day for 7 days. For treatment of tinea versicolor: Apply to affected areas and lather with a small amount of water. Allow product to remain on skin for 10 minutes, then rinse the body thoroughly. Repeat procedure once a day for 7 days.

The treatment for tinea versicolor is to apply selenium sulfide to the affected areas, lather with a small amount of water, and allow it to remain on the skin for 10 minutes before rinsing thoroughly. This procedure should be repeated once a day for 7 days 1 1.

  • Key points:
    • Apply to affected areas
    • Lather with a small amount of water
    • Remain on skin for 10 minutes
    • Rinse body thoroughly
    • Repeat once a day for 7 days

From the Research

Tinea versicolor is most effectively treated with oral fluconazole 300mg weekly for 2 weeks, as it has shown high efficacy and safety in recent studies. This treatment approach is supported by a study published in 2005 2, which demonstrated a 75% complete cure rate and 77.5% mycologic cure rate with oral fluconazole. The study also showed no adverse effects and no recurrence at the 12-week follow-up visit.

Treatment Options

  • Topical treatments, such as selenium sulfide 2.5% lotion or ketoconazole 2% shampoo, can be used for mild to moderate cases, but may have lower efficacy and higher recurrence rates compared to oral fluconazole.
  • Other oral antifungals, such as itraconazole, can also be effective, but may have a higher risk of side effects and interactions.
  • Maintenance therapy with selenium sulfide or ketoconazole shampoo may be useful in preventing recurrence, especially in humid climates or for individuals who sweat heavily.

Key Considerations

  • The choice of treatment should be based on the severity of the infection, patient preferences, and potential side effects.
  • It is essential to note that even after successful treatment, skin discoloration may persist for weeks or months as the skin tone gradually normalizes.
  • Recent studies, such as the one published in 2015 3, have highlighted the importance of antifungal treatment in managing tinea versicolor, and oral fluconazole has emerged as a highly effective and safe option.

References

Research

Oral fluconazole in the treatment of tinea versicolor.

The Journal of dermatology, 2005

Research

Antifungal Treatment for Pityriasis Versicolor.

Journal of fungi (Basel, Switzerland), 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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