From the FDA Drug Label
The dosage of Sodium Chloride Oral Solution 23.4% is predicated on the specific requirements of the patient based on clinical and laboratory information. Ages 9 to 50 4 ml (equivalent to 936 mg) Children under 9 years and adults over 50 years Consult a physician
The correct dosage of sodium chloride (NaCl) tablets for treating hyponatremia is not specified in the provided drug label for tablet form, but for oral solution. However, for the oral solution, the dosage is:
- 4 ml (equivalent to 936 mg) for patients aged 9 to 50.
- For children under 9 years and adults over 50 years, a physician should be consulted for the correct dosage 1.
Note: The provided label does not mention tablets, but an oral solution.
From the Research
The correct dosage of sodium chloride (NaCl) tablets for treating hyponatremia is 1-3 grams taken 3-4 times daily, with the goal of increasing serum sodium concentration by 6-8 mEq/L in 24 hours, as supported by the most recent study 2.
Key Considerations
- The dosage may vary based on the severity of the condition and individual patient factors, such as age, heart or kidney disease, and the underlying cause of hyponatremia.
- Treatment should be initiated under medical supervision with regular monitoring of serum sodium levels to avoid osmotic demyelination syndrome, a serious neurological complication.
- Patients should be advised to maintain adequate fluid intake but restrict free water consumption during treatment.
- The rate of sodium correction should not exceed 8-10 mEq/L in 24 hours, as recommended by 3 and 4.
Treatment Approach
- Sodium chloride tablets work by increasing serum sodium concentration, helping to restore normal fluid balance and cellular function.
- Treatment duration depends on response and should continue until sodium levels normalize, typically within days to weeks.
- Elderly patients and those with heart or kidney disease may require lower doses and more careful monitoring due to increased risk of fluid overload, as noted in 2.