Bromfed Dosing for 11.11 kg Child
For a child weighing 11.11 kg (approximately 2-6 years old based on typical weight-for-age), give 2.5 mL (½ teaspoonful) of Bromfed every 4 hours, not exceeding 6 doses in 24 hours. 1
Dosing Rationale
The FDA-approved dosing for Bromfed is age-based rather than weight-based 1. An 11.11 kg child typically falls within the 2 to under 6 years age range, which corresponds to the 2.5 mL dose. This provides:
- Brompheniramine maleate: 2 mg per dose
- Pseudoephedrine: 30 mg per dose
Key Clinical Considerations
Age vs. Weight Determination
- If the child is 2-6 years old: Use 2.5 mL every 4 hours
- If the child is under 2 years old (which would be unusual at 11.11 kg): Dosage must be established by a physician 1
- The weight of 11.11 kg most commonly corresponds to a 2-4 year old child, making the 2.5 mL dose appropriate
Maximum Daily Dosing
- Do not exceed 6 doses (15 mL total) in 24 hours 1
- This provides maximum daily doses of:
- Brompheniramine: 12 mg/day
- Pseudoephedrine: 180 mg/day
Safety Monitoring
Watch for anticholinergic effects from brompheniramine including:
- Sedation (common)
- Dry mouth
- Urinary retention
- Paradoxical CNS stimulation (especially in young children) 1
Watch for sympathomimetic effects from pseudoephedrine:
- Tachycardia
- Hypertension
- CNS stimulation
- Cardiac arrhythmias 1
Critical Drug Interactions
Avoid concurrent use with SSRIs or other serotonergic agents - the dextromethorphan component (if present in the formulation) can precipitate serotonin syndrome even at therapeutic doses 2. Verify the specific Bromfed formulation being used, as some contain dextromethorphan and others do not.
Common Pitfalls to Avoid
- Do not use total body weight for dosing - Bromfed uses age-based dosing per FDA labeling, not mg/kg calculations 1
- Do not round up to the next age bracket - use the age-appropriate dose, not weight-appropriate dose
- Do not exceed 6 doses per day - toxicity risk increases significantly with overdosing, particularly CNS effects in children 1