From the Research
Chasteberry (Vitex agnus-castus) is generally considered safe for most women to use for PMS symptoms, but it should be used with caution and preferably under healthcare supervision.
Key Considerations
- Typical dosages range from 20-40 mg of dried fruit extract daily, taken for at least three menstrual cycles to evaluate effectiveness, as supported by studies such as 1.
- Side effects are usually mild and may include headache, gastrointestinal discomfort, skin reactions, or menstrual changes.
- Women who are pregnant, breastfeeding, using hormonal contraceptives, or taking dopamine-related medications should avoid chasteberry due to potential interactions.
Mechanism of Action
- The herb works by affecting hormone levels, particularly prolactin, through its action on dopamine receptors in the pituitary gland, as explained in 2.
- This mechanism helps balance estrogen and progesterone levels, potentially reducing PMS symptoms like breast tenderness, mood swings, and irritability.
Efficacy and Safety
- A meta-analysis of double-blind randomised controlled trials, such as 1, found that VAC preparations were effective in reducing PMS symptoms, with women taking VAC being 2.57 times more likely to experience a remission in their symptoms compared to those taking the placebo.
- While many women report benefits, individual responses vary, and it's essential to purchase products from reputable manufacturers since herbal supplements aren't strictly regulated for quality or potency.