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Last updated: June 14, 2025View editorial policy

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Differential Diagnosis for Numbness and Tingling in Left Arm after Lumbar Puncture

  • Single most likely diagnosis:
    • Post-dural puncture headache (PDPH) with referred pain: This is the most common complication of lumbar puncture, and while it typically presents with a headache, it can also cause referred pain or numbness and tingling in the arms due to the decrease in cerebrospinal fluid pressure.
  • Other Likely diagnoses:
    • Traumatic nerve injury: Direct injury to nerves during the procedure can cause numbness and tingling.
    • Epidural or spinal hematoma: Although rare, bleeding into the epidural or spinal space can compress nerves, leading to numbness and tingling.
    • Chemical meningitis: Introduction of blood or other substances into the cerebrospinal fluid during the lumbar puncture can cause inflammation and irritation of the nerves.
  • Do Not Miss diagnoses:
    • Spinal epidural abscess: An infection in the epidural space can cause severe neurological deficits, including numbness and tingling, and is a medical emergency.
    • Subarachnoid hemorrhage: Bleeding into the subarachnoid space can cause sudden, severe symptoms, including numbness and tingling, and requires immediate medical attention.
  • Rare diagnoses:
    • Arachnoiditis: Inflammation of the arachnoid membrane can cause numbness, tingling, and other neurological symptoms, but is relatively rare as a complication of lumbar puncture.
    • Nerve root avulsion: Severe traction on the nerve roots during the procedure can cause avulsion, leading to numbness and tingling, but this is extremely rare.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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