From the Research
The recommended dosage of KSM-66 Ashwagandha extract for stress and anxiety relief is typically 300-600 mg per day, taken in divided doses, as supported by the most recent and highest quality study 1.
Key Considerations
- Most clinical studies showing benefits have used 600 mg daily, often split into two 300 mg doses taken in the morning and evening with meals.
- For best results, take KSM-66 consistently for at least 8-12 weeks, as the adaptogenic effects build over time.
- Start with a lower dose (300 mg daily) and increase gradually if needed to assess your tolerance.
- KSM-66 works by helping regulate cortisol levels and supporting the body's stress response systems, as evidenced by reduced cortisol levels in studies 2, 3.
- It contains a standardized concentration of withanolides, the active compounds responsible for ashwagandha's stress-relieving properties.
Important Notes
- While generally well-tolerated, some people may experience mild digestive upset, so taking it with food can help.
- If you're pregnant, nursing, taking medications, or have a medical condition (especially thyroid disorders), consult your healthcare provider before use as ashwagandha may interact with certain medications and conditions.
- A systematic review and meta-analysis of randomized controlled trials found that Ashwagandha supplementation significantly reduced anxiety and stress levels, with a favorable effect at doses of 300-600 mg/d 4.
- A recent study found that Ashwagandha root extract alleviated stress, anxiety, and improved quality of life in healthy adults by modulating stress hormones, with a dosage of 500 mg per day standardized for 2.5% withanolides 1.