Where can I download the latest (2025) autoimmune hepatitis clinical practice guideline PDF?

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Last updated: November 6, 2026 • View editorial policy

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Where to Download the 2025 Autoimmune Hepatitis Guidelines

The latest 2025 autoimmune hepatitis clinical practice guidelines are available from two major societies: the EASL (European Association for the Study of the Liver) guidelines published in the Journal of Hepatology 1 and the British Society of Gastroenterology (BSG) guidelines published in Gut 2.

Accessing the Guidelines

EASL Guidelines (2025)

  • Journal: Journal of Hepatology
  • Access: Available through the Journal of Hepatology website or EASL's official website (www.easl.eu)
  • Copyright: © 2025 European Association for the Study of the Liver, published by Elsevier B.V. 1
  • Scope: Comprehensive guidance on diagnosis and management of AIH in both adults and children, including variants, specific forms, AIH-associated cirrhosis, portal hypertension surveillance, hepatocellular carcinoma monitoring, and liver transplantation 1

BSG Guidelines (2025)

  • Journal: Gut
  • Access: Available through the Gut journal website or BSG's official website
  • Scope: Covers diagnosis and management with emphasis on UK practice, includes patient summary section, and provides clinical research priorities 2
  • Unique features: Developed by multidisciplinary group including two patients with AIH, focuses on personalized care approach 2

Key Differences Between the Two Guidelines

Both guidelines were published in 2025 and represent the most current evidence-based recommendations. The EASL guidelines provide a European perspective with global applicability, while the BSG guidelines offer UK-specific recommendations with particular attention to service organization and quality assessment 2.

Important Context

These 2025 guidelines represent significant updates from previous versions (the last BSG guideline was from 2011), incorporating advances in understanding AIH epidemiology, diagnosis, and management 2. Both emphasize that AIH is becoming more common than previously recognized, with global pooled incidence of 1.28 cases/100,000 inhabitant-years and prevalence of 15.65 cases/100,000 inhabitants 1.

References

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.