JORNAY PM Adult Starting Dose
The recommended starting dose of JORNAY PM for adults is 20 mg once daily, taken orally in the evening between 6:30 PM and 9:30 PM (most commonly at 8:00 PM). 1
Key Dosing Parameters
Initial Dosing:
- Start at 20 mg once daily in the evening
- Do NOT take in the morning
- Initial timing should be 8:00 PM, with flexibility to adjust between 6:30 PM and 9:30 PM based on individual response 1
Titration Schedule:
- Increase weekly in 20 mg increments if needed
- Maximum studied dose is 100 mg daily (doses above this are not recommended)
- Maintain consistent timing once optimal administration time is determined 1
Administration Considerations
Food Effects:
- Take consistently either with food or without food (choose one approach and maintain it) 1
Formulation Options:
- May swallow capsule whole, OR
- Open capsule and sprinkle entire contents onto applesauce (consume immediately without chewing; do not divide dose) 1
Critical Warnings
Do not substitute JORNAY PM for other methylphenidate products on a milligram-per-milligram basis - JORNAY PM has different pharmacokinetic properties and methylphenidate base composition compared to other formulations 1
Important Caveat: If switching from another methylphenidate product, discontinue that treatment first and titrate JORNAY PM using the standard 20 mg starting dose and weekly titration schedule described above 1
Pretreatment Requirements
Before initiating JORNAY PM, assess for:
- Cardiac disease (careful history, family history of sudden death/ventricular arrhythmia, physical exam)
- Family history and clinical evaluation for motor/verbal tics or Tourette's syndrome 1