From the Guidelines
You can cut Ambien (zolpidem) in half, but only the immediate-release tablets, not the extended-release (CR) versions, and it is recommended to consult with your healthcare provider before changing your dosage. The standard immediate-release tablets (5mg or 10mg) can be split if needed to adjust your dose, as indicated in the clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults 1. Splitting may be appropriate if you're experiencing side effects at your current dose or if your doctor wants you to start with a lower dose. When cutting the tablet, use a pill cutter for accuracy rather than a knife or scissors.
Some key points to consider when taking Ambien include:
- Ambien is a controlled substance prescribed for short-term treatment of insomnia and should be taken exactly as directed 1.
- The medication works by enhancing the effect of GABA, a neurotransmitter that promotes sleep, so even half a dose will have sedative effects.
- Ambien can cause next-day impairment, so take it only when you have a full night's sleep opportunity ahead of you.
- It is essential to follow the recommended dosage and usage guidelines to minimize the risk of adverse effects and ensure the medication's effectiveness.
It is crucial to prioritize your health and safety when taking Ambien, and consulting with your healthcare provider before making any changes to your dosage is highly recommended. They can provide personalized guidance and help you make informed decisions about your treatment plan.
From the Research
Cutting Ambien in Half
- There is no direct evidence in the provided studies that addresses the specific question of cutting Ambien (zolpidem) in half.
- However, the studies discuss the efficacy, safety, and dosing of zolpidem in the treatment of insomnia 2, 3, 4, 5, 6.
- The recommended dosage of zolpidem is 10 mg/day for adults and 5 mg/day for the elderly or patients with hepatic impairment 3.
- It is not clear if cutting the tablet in half would affect the efficacy or safety of the medication, but it is generally recommended to follow the manufacturer's prescribing information and consult with a healthcare professional before altering the dosage or form of the medication.
- Some studies suggest that zolpidem is effective and well-tolerated in patients with insomnia, with minimal risk of withdrawal or abuse 4, 5.
- However, other studies report that zolpidem can be associated with rebound insomnia, complex sleep-related behaviors, and next-day residual effects 4.