From the Guidelines
A laboratory result of "lacking normal platelet" (Lac nt platelet) count means you have a low platelet count, also known as thrombocytopenia, which increases the risk of bleeding and requires medical attention. This condition is characterized by a platelet count below 150,000 per microliter of blood, with normal ranges between 150,000 to 450,000 platelets per microliter 1. Symptoms may include easy bruising, prolonged bleeding from cuts, nosebleeds, bleeding gums, blood in urine or stool, or tiny red spots on the skin called petechiae.
Causes and Treatment
The causes of low platelets can be due to decreased production in bone marrow, increased destruction, or increased consumption 1. Treatment depends on the cause and severity, ranging from monitoring mild cases to medications like corticosteroids, immune globulin, or thrombopoietin receptor agonists for more severe cases. In emergencies with very low counts, platelet transfusions may be necessary, as supported by the European guideline on management of major bleeding and coagulopathy following trauma: sixth edition 1.
Importance of Monitoring
Regular follow-up blood tests are important to monitor platelet levels and treatment effectiveness. It is crucial to note that a low platelet count has been consistently associated with both morbidity and mortality, especially in trauma patients 1. Therefore, prompt medical evaluation and management are essential to prevent complications and improve quality of life.
From the Research
Laboratory Result of Lacking Normal Platelet Count
A laboratory result of lacking normal platelet (Lac nt platelet) count refers to a condition where the platelet count is less than the normal range.
- The normal platelet count range is typically considered to be between 150,000/μL and 450,000/μL 2, 3.
- A platelet count less than 150,000/μL is defined as thrombocytopenia, which can be caused by decreased platelet production, sequestration of platelets, or increased destruction of platelets 2.
- Thrombocytopenia can be acute or chronic, congenital or acquired, and can be associated with life-threatening bleeding and thrombotic complications 3.
Possible Causes of Thrombocytopenia
The causes of thrombocytopenia are varied and can include:
- Infections 2, 4
- Malignancy 2
- Liver disease 2
- Autoimmune disorders 2
- Disseminated intravascular coagulation 2
- Pregnancy 2
- Medications 2
- Coagulation disorders 2
- Immune thrombocytopenia, as seen in some cases of COVID-19 4
Diagnosis and Evaluation
The diagnosis and evaluation of thrombocytopenia involve a comprehensive history and physical examination, as well as laboratory tests such as: