What causes suicidality in Premenstrual Dysphoric Disorder (PMDD)?

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From the Guidelines

Suicidality in Premenstrual Dysphoric Disorder (PMDD) is primarily caused by the severe mood symptoms, such as depressed mood, that occur in the disorder.

Key Factors

  • The study 1 describes PMDD as characterized by a pattern of mood symptoms, including depressed mood, which can contribute to suicidality.
  • The mood symptoms in PMDD, such as depressed mood, can be severe and may lead to suicidal thoughts or behaviors.
  • The cyclical nature of PMDD, with symptoms worsening before menses and improving after, can also contribute to feelings of hopelessness and despair, increasing the risk of suicidality.

Relevant Details

  • The diagnosis of PMDD, as described in the study 1, highlights the importance of recognizing the pattern of symptoms that occur in relation to the menstrual cycle.
  • The severity of mood symptoms, such as depressed mood, can vary from person to person, but can be severe enough to lead to suicidality in some cases.
  • It is essential to note that PMDD is a distinct disorder from other mental health conditions, and its unique characteristics, such as the cyclical pattern of symptoms, should be considered when assessing and managing suicidality.

From the Research

Suicidality in Premenstrual Dysphoric Disorder (PMDD)

  • Women with PMDD are at a higher risk of suicidality, with a nearly seven times higher risk of suicide attempt and almost four times higher risk of suicidal ideation compared to women without premenstrual disturbances 2.
  • The prevalence of current suicidal ideation in women with confirmed PMDD is nearly 40% 3.
  • Suicidal thoughts, ideation, plans, and attempts are strongly associated with experiences of PMDD, independent of psychiatric co-morbidities 4.

Factors Associated with Suicidality in PMDD

  • Previous psychological treatment for PMDD and higher depressive symptoms in the late luteal phase are positively associated with current suicidal ideation 3.
  • Higher ratings of self-rated health are associated with lower odds ratios for current suicidal ideation 3.
  • Personality traits such as impulsivity, aggressiveness/hostility, hopelessness, trait anger, affect intensity, and emotional lability are associated with PMS/PMDD 5.
  • Factors associated with suicide risk in young women with PMDD include current panic disorder, non-white skin color, greater severity of depressive symptoms, and history of childhood trauma 6.

Clinical Implications

  • Women with PMDD should be considered a high-risk group for suicidality, and identifying and treating symptoms are vital in reducing suicide attempts 4.
  • Clinicians should be aware of the association between PMS/PMDD and trait anger, and address this in treatment plans 5.
  • Screening for suicidal ideation and behavior should be routine in women with PMDD, particularly in those with associated risk factors 2, 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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