How is percutaneous vertebroplasty (PVP) performed?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 12, 2026 • View editorial policy

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.

How Percutaneous Vertebroplasty (PVP) is Performed

Percutaneous vertebroplasty is performed by injecting bone cement (polymethylmethacrylate/PMMA) through a large-bore needle into a fractured vertebral body under fluoroscopic guidance, typically using a transpedicular approach with the patient prone under local anesthesia with moderate sedation. 1

Pre-Procedure Setup and Patient Positioning

The procedure requires a suite large enough to accommodate:

  • High-quality biplane fluoroscopy (advisable, particularly during cement delivery)
  • Patient monitoring equipment (pulse oximetry, blood pressure)
  • Cardiopulmonary resuscitation equipment
  • Rapid availability of CT and/or MRI for complications 1

Patient positioning: Prone position under local anesthesia combined with moderate sedation in most cases 1. General anesthesia may be used for patients at high risk of airway/respiratory complications with prone positioning or those with significant pre-procedural narcotic requirements 1. However, keeping the patient awake is preferable as it allows real-time feedback about increasing pain or neurologic dysfunction that can alert the operator to potential complications 1.

Needle Placement Technique

Approach Selection

  • Transpedicular approach is standard (unilateral or bilateral)
  • The choice between unilateral vs. bilateral can be determined by preoperative CT measurements 2
  • CT three-dimensional positioning can identify the optimal trajectory for passing through the lateral mass of the lamina and pedicle to reach the vertebral body 3

Needle Insertion

  • A 13-gauge needle is typically used 3
  • Skin entry point and puncture angles (both transverse and sagittal planes) should be determined using preoperative CT imaging software 2
  • Fluoroscopic guidance directs needle placement into the fractured vertebral body 1, 4
  • Pre-procedural imaging should be available in the procedure room to ensure correct vertebral levels are treated 1

Cement Injection

  • PMMA (polymethylmethacrylate) bone cement is injected through the needle into the vertebral body 4, 5, 6
  • Injection is performed under continuous fluoroscopic monitoring to detect cement leakage early 1
  • The cement reinforces the compressed vertebral segment 5

Important caveat: CT-guided techniques may offer lower complication risk compared to conventional fluoroscopic approaches due to more precise instrument placement and earlier detection of small cement leakages 5.

Post-Procedure Care

  • Patient is placed in supine position for approximately 1 hour while cement hardens 4
  • Period of bed rest and observation tailored to clinical circumstances 1
  • Vital signs and lower limb neurological function assessed at regular intervals 1
  • Supervised ambulation after appropriate observation period 1

Critical Technical Points

Monitoring during the procedure:

  • Vital signs monitoring is essential
  • Pulse oximetry and blood pressure measurement during sedation delivery
  • Drug delivery and monitoring by certified nursing personnel, nurse anesthetists, or anesthesiologists 1

Patient identity verification: Follow local hospital practices for confirmation of patient identity, procedure to be performed, procedural site, and consent 1

Common Pitfalls

Cement leakage is the most frequent complication—small amounts are common (72% of treated vertebrae in one study showed leaks on post-procedural CT, though most remained asymptomatic) 1. Continuous fluoroscopic monitoring during injection is critical to minimize symptomatic leakage that could cause nerve compression or pulmonary embolism 1, 4.

Related Questions

What is the recommended duration of dual antiplatelet therapy after iliac artery stent placement?
Is there a specific timing for hormone laboratory testing in a woman in her 40s who has had a hysterectomy but still has her ovaries?
What is the characteristic timing of diastolic murmurs relative to the heart sounds?
What is the likely cause and recommended treatment for a Gram stain showing few squamous epithelial cells, more than 25 white blood cells per low‑power field, and a few Gram‑positive cocci in clusters?
Is Vicryl (polyglactin 910) an absorbable suture?
Is sumatriptan safe to use in a patient with non‑ST‑elevation myocardial infarction (NSTEMI)?
What is the expected duration of healing for an osteoporotic lumbar compression fracture in an elderly patient?
What markers are evaluated in the leukemia/lymphoma flow‑cytometric immunophenotyping panel?
Please analyze a clinical case from internal medicine and critical care perspectives, identifying the primary problems, generating differential diagnoses with pathophysiologic reasoning, interpreting laboratory, ECG, and arterial blood gas results, recommending additional investigations, and outlining an initial management plan with drug dosing and renal dose adjustments, supported by clinical guidelines.
What is the recommended management for persistent ringworm (tinea corporis) that has not resolved after six weeks of therapy?
For a patient with total cholesterol 210 mg/dL and LDL 117 mg/dL who has generalized muscle pain and nocturnal lower‑extremity cramps, what is the recommended approach to initiating or managing pravastatin 10 mg?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.