What is the dosage of Mebendazole (antiparasitic medication) for pinworm infection?

From the Guidelines

The recommended dosage of Mebendazole for pinworm infection is 100 mg as a single dose. This dosage is applicable for children over 2 years of age and adults, as stated in the study published in the Journal of Infection 1. The treatment works by preventing the worms from absorbing nutrients, causing them to die and be eliminated from the body. Some key points to consider when treating pinworm infection with Mebendazole include:

• Treating all household members simultaneously, even if they don't show symptoms, as pinworm is highly contagious
• Implementing hygiene measures such as washing bedding and underwear in hot water, regular handwashing, keeping fingernails short, and avoiding nail-biting to prevent reinfection
• Being aware of potential side effects, which are typically mild and may include abdominal pain, diarrhea, or nausea
• Considering a second dose 2 weeks later to prevent reinfection, although the study 1 only mentions a single dose of 100 mg. It's essential to note that children under 2 years should only receive Mebendazole under medical supervision with adjusted dosing. If symptoms persist after treatment, it's crucial to consult a healthcare provider as retreatment or alternative medication may be necessary.

From the FDA Drug Label

DOSAGE AND ADMINISTRATION The same dosage schedule applies to children and adults. ... Pinworm (enterobiasis) ... Dose 1 tablet, once The dosage of Mebendazole for pinworm infection is 1 tablet, once 2.

From the Research

Dosage of Mebendazole for Pinworm Infection

The dosage of Mebendazole for pinworm infection is as follows:

• 100 mg given in a single dose and repeated in two weeks 3
• This dosage is applicable for both adults and children
• Mebendazole is an adulticidal and ovicidal drug, making it effective against both adult worms and eggs

Treatment Considerations

Some important considerations for the treatment of pinworm infection with Mebendazole include:

• Treatment of all household members should be considered, especially if there are multiple or repeated symptomatic infections 3
• Good personal hygiene, such as frequent handwashing, is important to prevent reinfection 3
• Mebendazole is not recommended for pregnant women, and pyrantel pamoate is preferred instead 3

Efficacy of Mebendazole

Mebendazole has been shown to be effective in treating pinworm infections, with a high cure rate and significant reduction in egg output 3, 4

• A single dose of 100 mg Mebendazole has been shown to be effective in reducing egg output by over 80% 4
• Mebendazole is well-tolerated and has a broad spectrum of activity, making it a useful drug for treating multiple infestations 5