From the Research
Xolair (omalizumab) is not typically known to cause taste disturbances as a common side effect. While many medications can affect taste perception, altered taste (dysgeusia) is not listed among the common or even rare side effects of Xolair in clinical studies or post-marketing surveillance 1, 2, 3, 4, 5. Xolair is a monoclonal antibody that works by binding to IgE antibodies in the bloodstream, preventing them from triggering allergic reactions, particularly in conditions like severe asthma and chronic urticaria (hives). This mechanism of action does not directly involve taste receptors or the neurological pathways responsible for taste perception.
Key Points to Consider
- The most recent and highest quality study on the topic is from 2024, which focused on the use of omalizumab for the treatment of multiple food allergies, but did not mention taste disturbances as a side effect 3.
- Other studies have also not reported taste disturbances as a common side effect of Xolair 1, 2, 4, 5.
- If you are experiencing changes in taste while taking Xolair, it's essential to discuss this with your healthcare provider as it may be related to another medication you're taking, an underlying condition, or possibly an uncommon reaction to Xolair that should be documented.
- Your doctor can help determine the cause and may consider adjusting your treatment if necessary. Some potential considerations for changes in taste include:
- Other medications that may be contributing to the taste disturbance
- Underlying conditions that could be affecting taste perception
- Uncommon reactions to Xolair that have not been widely reported in clinical studies or post-marketing surveillance.