Which probiotics (Probiotic Bacteria) improve Gastroesophageal Reflux Disease (GERD)?

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Last updated: June 16, 2025View editorial policy

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From the Research

Probiotics containing Lactobacillus and Bifidobacterium species, such as Lactobacillus reuteri DSM 17938 and Bifidobacterium lactis, may help improve Gastroesophageal Reflux Disease (GERD) symptoms. The most recent and highest quality study, a systematic review and meta-analysis published in 2022 1, found that probiotic interventions, including probiotic yoghurt, can improve GERD symptoms. Another study published in 2020 2 also found that probiotics can be beneficial for GERD symptoms, such as regurgitation and heartburn.

The mechanisms by which probiotics improve GERD symptoms are not fully understood, but they may include:

  • Restoring normal gut microbiota balance
  • Strengthening the lower esophageal sphincter
  • Reducing inflammation in the digestive tract
  • Improving gastric emptying
  • Decreasing the growth of harmful bacteria that produce gas and increase abdominal pressure

To evaluate the effectiveness of probiotics for GERD, it is recommended to take a probiotic containing at least 1 billion CFU (colony-forming units) daily for at least 4-8 weeks. Some people may experience temporary bloating or gas when starting probiotics, so beginning with a lower dose and gradually increasing it can help minimize these effects. While probiotics can be a helpful complementary approach, they should not replace conventional GERD treatments like proton pump inhibitors or lifestyle modifications.

It is essential to note that the evidence for the use of probiotics in GERD is still limited, and more research is needed to fully understand their effects. However, based on the available evidence, probiotics containing Lactobacillus and Bifidobacterium species may be a useful adjunctive treatment for GERD symptoms.

Key points to consider when using probiotics for GERD include:

  • Choosing a probiotic with multiple strains, including Lactobacillus and Bifidobacterium species
  • Taking a sufficient dose (at least 1 billion CFU daily) for an adequate duration (at least 4-8 weeks)
  • Starting with a lower dose and gradually increasing it to minimize potential side effects
  • Using probiotics as a complementary approach, in addition to conventional GERD treatments.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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