From the Research
Low vitamin D levels have been linked to an increased risk of headaches, particularly migraines, as evidenced by a recent study published in 2025 1. This study found a significant negative correlation between serum vitamin D levels and the prevalence of migraine in American adults. The exact mechanism is not fully understood, but it's thought that vitamin D may play a role in reducing inflammation, regulating pain pathways, and affecting serotonin levels in the brain. Some key points to consider:
- Normal vitamin D levels should be above 30 ng/mL (75 nmol/L) 2.
- If you're deficient, supplementation typically involves taking vitamin D3 (cholecalciferol) at doses of 1,000-2,000 IU daily for maintenance or higher doses (such as 5,000 IU daily for 8-12 weeks) for correction of deficiency, under medical supervision 3.
- It's essential to address other potential headache triggers and consult with a healthcare provider before starting supplements, as excessive vitamin D can cause toxicity.
- The relationship between vitamin D and headaches is not definitively established, but the current evidence suggests that supplementation may be beneficial in reducing the frequency of headaches, especially in individuals with vitamin D deficiency 4. The most recent and highest quality study 1 supports the idea that vitamin D supplementation may be helpful in reducing the frequency and severity of migraines, making it a potential treatment option for individuals with low vitamin D levels and frequent headaches.