From the Research
The treatment for an inflamed seborrheic keratosis typically involves observation and symptomatic care as these growths often resolve on their own. For mild inflammation, gentle cleansing with mild soap and water is recommended, followed by applying a thin layer of petroleum jelly to protect the area. Over-the-counter hydrocortisone cream (0.5-1%) can be applied twice daily for up to one week to reduce inflammation and itching, as suggested by the use of topical corticosteroids in similar skin conditions 1. For pain relief, acetaminophen (Tylenol) 500-1000mg every 6 hours or ibuprofen (Advil, Motrin) 400-600mg every 6-8 hours can be taken as needed. If the inflammation is severe, persists beyond 1-2 weeks, or if the growth shows signs of infection (increasing redness, warmth, pus, or spreading redness), medical attention should be sought promptly. A healthcare provider may prescribe stronger anti-inflammatory medications or antibiotics if infection is present. In some cases, they might recommend removal of the growth through cryotherapy (freezing), curettage (scraping), or electrocautery (burning), as outlined in recent updates on the treatment options for seborrheic keratosis 2. It's also important to note that while seborrheic keratoses are benign, rare cases of melanoma arising within these lesions have been reported, highlighting the importance of thorough examination and potential biopsy for atypical or persistent lesions 3. Inflamed seborrheic keratoses typically result from friction, irritation, or minor trauma to these benign skin growths, and treatment aims to reduce inflammation while the body's natural healing processes occur. Given the potential for diagnostic challenges, especially with inflamed seborrheic keratoses that may mimic malignancies upon dermoscopic examination 4, a cautious approach that includes consideration for histopathological examination in uncertain cases is prudent. The choice of treatment should prioritize methods that minimize the risk of scarring and post-procedure depigmentation, considering the cosmetic concerns often associated with these lesions, particularly when they occur on the face 2, 5.