What are the as-needed medications for anxiety?

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Last updated: June 17, 2025View editorial policy

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From the FDA Drug Label

Alprazolam tablets are indicated for the management of anxiety disorder Lorazepam Oral Concentrate is a prescription medicine used: to treat anxiety disorders for the short-term relief of the symptoms of anxiety

As-needed medications for anxiety include:

  • Alprazolam 1
  • Lorazepam 2 These medications are used for the short-term relief of symptoms of anxiety.

From the Research

As-needed medications for anxiety include benzodiazepines like lorazepam (0.5-2mg), alprazolam (0.25-1mg), clonazepam (0.5-2mg), and diazepam (2-10mg), which can be taken when anxiety symptoms arise, but due to their potential for dependence and tolerance, they should be used with caution and under the guidance of a healthcare provider 3. When considering as-needed medications for anxiety, it's essential to weigh the benefits and risks of each option. Benzodiazepines, such as those mentioned above, work quickly to reduce anxiety symptoms by enhancing the effect of GABA, an inhibitory neurotransmitter that reduces brain activity. However, their use should be limited due to the potential for dependence and tolerance, as highlighted in a study comparing SSRIs and benzodiazepines for panic disorder 4. Other options for as-needed anxiety medications include:

  • Beta-blockers like propranolol (10-40mg) to manage physical symptoms like trembling and rapid heartbeat
  • Antihistamines like hydroxyzine (25-50mg) as a non-addictive alternative that can reduce anxiety while causing sedation, although its effectiveness is still a topic of debate 5 It's crucial to use these medications only when truly necessary and in conjunction with other anxiety management strategies, such as therapy, relaxation techniques, and lifestyle modifications. A healthcare provider should be consulted before starting any medication to determine the most appropriate option based on specific symptoms, medical history, and other medications being taken. The most recent and highest quality study on the topic, published in 2020, recommends selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) as first-line treatments for anxiety disorders, with benzodiazepines not recommended for routine use due to their potential for addiction 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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