What is the protocol for performing microneedling of the scalp with SkinPen (microneedling device)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Microneedling of the scalp with SkinPen should be performed by mapping out areas of hair loss and injecting into the scalp at a 90-degree angle between 2 to 4 mm depth, with treatments spaced 4 to 6 weeks apart for a total of 3 sessions per annum, as this protocol has been shown to be effective in promoting hair growth. When performing microneedling, it is essential to follow a specific protocol to ensure safety and effectiveness. The treatment area should be cleansed with an antiseptic solution, and a topical anesthetic cream can be applied to minimize discomfort 1. The SkinPen device should be used with a needle depth suitable for scalp treatments, and a gliding medium such as sterile hyaluronic acid serum or saline solution should be applied to facilitate the procedure.

Some key considerations when performing microneedling of the scalp include:

  • Mapping out areas of hair loss to target treatment effectively 1
  • Injecting into the scalp at a 90-degree angle between 2 to 4 mm depth, with injections 1 cm apart 1
  • Spacing treatments 4 to 6 weeks apart for a total of 3 sessions per annum, with maintenance sessions every 6 months 1
  • Ensuring the patient has not applied any hair products and has shampooed and detangled their hair before the session 1
  • Taking excellent before and after photos to track progress 1

It is also crucial to prepare everything before starting the procedure, including marking out the area to be treated and ensuring optimal positioning to access the scalp from all angles 1. By following this protocol and taking the necessary precautions, microneedling with SkinPen can be a safe and effective treatment for promoting hair growth and improving scalp health, as it stimulates the body's natural wound healing process, increasing blood flow to hair follicles and promoting the production of collagen and growth factors 1.

From the Research

Protocol for Microneedling of the Scalp with SkinPen

The protocol for performing microneedling of the scalp with SkinPen involves several steps:

  • Preparation: The scalp should be cleaned and prepared for the procedure to minimize the risk of infection 2.
  • Anesthesia: Topical anesthesia may be applied to the scalp to reduce discomfort during the procedure.
  • Microneedling: The SkinPen device is used to create micro-injuries in the scalp, which stimulates collagen formation, neovascularization, and growth factor production 3.
  • Treatment parameters: The treatment parameters, such as the depth of penetration and the number of sessions, may vary depending on the individual's condition and response to treatment 4, 5.
  • Combination therapy: Microneedling may be combined with other hair growth promoting therapies, such as minoxidil, to enhance its effectiveness 6, 5.

Safety Considerations

The safety profile of microneedling is generally considered to be good, with most reported adverse events being transient and resolving quickly 2. However, caution should be taken in patients with active infections, darker skin types, and metal allergies. The most common reported adverse events include:

  • Transient erythema/edema and pain
  • Postinflammatory hyperpigmentation (PIH)
  • Dry skin/exfoliation
  • Lymphadenopathy
  • Irritant contact dermatitis

Efficacy of Microneedling for Hair Loss

The efficacy of microneedling for hair loss has been studied in several clinical trials, with promising results 3, 6, 5. Microneedling has been shown to increase total hair count and improve hair density, especially when combined with other hair growth promoting therapies. However, further studies are needed to determine the optimal treatment protocol and to fully establish the safety and efficacy of microneedling for hair loss.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Safety Profile for Microneedling: A Systematic Review.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2021

Research

Microneedling for the treatment of hair loss?

Journal of the European Academy of Dermatology and Venereology : JEADV, 2018

Research

Microneedling for Hair Loss.

Journal of cosmetic dermatology, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.