Differential Diagnosis for Eosinophilia with Eczema
- Single Most Likely Diagnosis
- Atopic Dermatitis (Eczema) with secondary eosinophilia: This is the most likely diagnosis as atopic dermatitis is a common condition that often presents with eosinophilia due to the allergic and inflammatory nature of the disease.
- Other Likely Diagnoses
- Allergic Contact Dermatitis: This condition can also cause eosinophilia and presents with eczematous lesions, although the distribution and history may differ from atopic dermatitis.
- Hypereosinophilic Syndrome (HES): Although less common, HES can present with skin manifestations including eczema and significant eosinophilia.
- Do Not Miss Diagnoses
- Lymphoma (e.g., Cutaneous T-cell Lymphoma): While rare, lymphomas can present with skin lesions resembling eczema and eosinophilia, making them critical not to miss due to their severe prognosis.
- Parasitic Infections: Certain parasitic infections can cause eosinophilia and skin lesions. Missing these diagnoses could lead to untreated infections with potentially severe consequences.
- Rare Diagnoses
- Eosinophilic Pustular Folliculitis: A rare condition characterized by eosinophilia and follicular papules or pustules, which could be mistaken for eczema.
- Omenn Syndrome: A rare form of severe combined immunodeficiency that presents with eczema, eosinophilia, and lymphadenopathy, highlighting the importance of considering immunodeficiencies in severe or atypical cases.