From the FDA Drug Label
VRAYLAR capsules are intended for oral administration only. The FDA drug label does not answer the question.
From the Research
No, you should not open Vraylar (cariprazine) capsules to administer in water. Vraylar capsules should be swallowed whole and should not be opened, crushed, or chewed. Opening the capsule could affect how the medication is absorbed by your body, potentially altering its effectiveness or safety profile. The medication is designed with specific release characteristics that may be compromised if the capsule is opened.
If you're having difficulty swallowing the capsule, contact your healthcare provider to discuss alternative options or formulations that might be more suitable for your needs. They might be able to recommend a different medication or administration method. Vraylar is an atypical antipsychotic medication used to treat schizophrenia and bipolar disorder, and maintaining its intended delivery system is important for proper treatment outcomes and minimizing side effects. According to a study on the manipulation of tablets and capsules, such as opening capsules and dispersing in water, it is not a recommended practice due to potential alterations in drug absorption and effectiveness 1.
Some key points to consider:
- Vraylar has specific release characteristics that may be compromised if the capsule is opened 2.
- Opening the capsule could affect how the medication is absorbed by your body, potentially altering its effectiveness or safety profile 3.
- If you're having difficulty swallowing the capsule, contact your healthcare provider to discuss alternative options or formulations that might be more suitable for your needs.
- Vraylar is an atypical antipsychotic medication used to treat schizophrenia and bipolar disorder, and maintaining its intended delivery system is important for proper treatment outcomes and minimizing side effects 4.