From the FDA Drug Label
Signs and symptoms reported in the literature after caffeine overdose in preterm infants include ... fine tremor of the extremities, hypertonia, opisthotonos, tonic-clonic movements, The caffeine tablets can cause muscle twitching, as evidenced by symptoms such as fine tremor of the extremities, hypertonia, tonic-clonic movements reported in the literature after caffeine overdose 1.
From the Research
Yes, Pro Plus (caffeine) tablets can cause muscle twitching. Caffeine is a stimulant that affects the central nervous system, and when consumed in high doses, it can lead to various side effects including muscle twitches or fasciculations. These twitches typically occur because caffeine increases the release of calcium within muscle cells and enhances nerve activity, which can cause involuntary muscle contractions. The standard Pro Plus tablet contains 50mg of caffeine, and consuming multiple tablets or combining them with other caffeine sources like coffee or energy drinks increases the risk of experiencing these effects. Most people may notice twitching when exceeding 400mg of caffeine daily (equivalent to about 8 Pro Plus tablets) 2.
Key Points to Consider
- Caffeine's stimulant effect on the central nervous system can lead to muscle twitching or fasciculations.
- High doses of caffeine, typically above 400mg per day, increase the risk of muscle twitching.
- Combining Pro Plus tablets with other sources of caffeine can exacerbate this risk.
- Underlying conditions such as anxiety disorders or heart problems may be worsened by caffeine consumption.
Recommendations
If you experience persistent muscle twitching after taking caffeine tablets, it's advisable to:
- Reduce your intake of caffeine.
- Consult with a healthcare provider, especially if you have underlying conditions that caffeine might exacerbate.
- Be aware of the total amount of caffeine you consume from all sources, including coffee, energy drinks, and certain medications.
Given the potential for muscle twitching and other side effects, cautious use of Pro Plus tablets is recommended, with attention to overall caffeine intake and potential interactions with other health conditions 3, 4.