Differential Diagnosis
- Single most likely diagnosis
- Prader-Willi Syndrome (PWS): This diagnosis is likely due to the combination of low birth weight, poor scholastic performance, hyperphagia, early onset of diabetes, short stature, and oligomenorrhea. The absence of retinitis pigmentosa and limb abnormalities does not rule out PWS, as these features are not universally present.
- Other Likely diagnoses
- Turner Syndrome: Although the patient has attained menarche, Turner Syndrome can present with short stature, oligomenorrhea, and diabetes. The lack of characteristic physical features and normal motor milestones do not exclude this diagnosis.
- Polycystic Ovary Syndrome (PCOS): The patient's hyperphagia, early onset of diabetes, and oligomenorrhea could be consistent with PCOS. However, the short stature and poor scholastic performance are not typical features of PCOS.
- Do Not Miss
- Congenital Hypopituitarism: This diagnosis could explain the short stature, oligomenorrhea, and diabetes. Although the patient has attained menarche, partial hypopituitarism could still be present.
- Pseudohypoparathyroidism: This condition can cause short stature, obesity, and diabetes. The absence of characteristic physical features does not rule out this diagnosis.
- Rare diagnoses
- Bardet-Biedl Syndrome: Although the patient does not have retinitis pigmentosa or limb abnormalities, some forms of Bardet-Biedl Syndrome may not exhibit these features. The combination of obesity, diabetes, and oligomenorrhea could be consistent with this diagnosis.
- Albright Hereditary Osteodystrophy: This rare condition can cause short stature, obesity, and diabetes. The absence of characteristic physical features does not rule out this diagnosis.