From the Research
Patients taking Humira (adalimumab) should take extra precautions against sun exposure as they face an increased risk of skin reactions, including sunburn and potentially skin cancer. Humira is a TNF-alpha inhibitor that suppresses parts of the immune system, which can make the skin more vulnerable to UV damage 1. When outdoors, patients should apply broad-spectrum sunscreen with SPF 30 or higher every two hours, wear protective clothing including long sleeves and wide-brimmed hats, seek shade especially between 10 AM and 4 PM, and wear UV-blocking sunglasses. Regular skin self-examinations are important, looking for any new growths, changes to existing moles, or unusual skin patches. Patients should report any concerning skin changes to their healthcare provider promptly. These precautions are particularly important because immunosuppressive medications like Humira can potentially increase the risk of developing certain types of skin cancer, including melanoma and non-melanoma skin cancers, due to the reduced immune surveillance against abnormal cells. Some studies have shown that extensive sun exposure does not have a protective effect on internal cancers, and may even increase the risk of skin cancer 2. Additionally, young cancer survivors, who may be taking immunosuppressive medications like Humira, often receive significant sun exposure and do not practice recommended sun protection 3. It is essential for patients taking Humira to be aware of the risks associated with sun exposure and take necessary precautions to protect their skin. The most common side effects of adalimumab are injection site reactions, but it can also increase the risk of rare serious infections, including skin infections 4. Overall, patients taking Humira should be cautious when exposed to the sun and take steps to protect their skin from UV damage.