What is the treatment for de Quervain tenosynovitis?

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Last updated: June 18, 2025View editorial policy

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From the Research

The most effective treatment for de Quervain tenosynovitis is corticosteroid injections into the tendon sheath, with success rates of 50-80% after one or two injections, as supported by the study published in 2014 1. The treatment for de Quervain tenosynovitis typically begins with conservative measures, including:

  • Rest, ice application, and immobilization of the thumb and wrist with a splint or brace for 2-6 weeks to reduce inflammation and pain
  • Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (400-800mg three times daily) or naproxen (250-500mg twice daily) to manage pain and reduce inflammation If these measures are insufficient, corticosteroid injections into the tendon sheath (typically 1ml of 40mg/ml methylprednisolone or equivalent with 1ml of lidocaine) may provide significant relief, with success rates of 50-80% after one or two injections, as shown in the study published in 2014 1. Additional treatment options may include:
  • Physical therapy focusing on gentle stretching and strengthening exercises for the thumb and wrist to restore function and prevent recurrence
  • Occupational therapy to modify activities that aggravate the condition
  • Surgical release of the first dorsal compartment for cases resistant to conservative treatment after 4-6 months, as discussed in the study published in 2015 2. It's worth noting that a systematic review published in 2020 3 found that laser therapy and therapeutic ultrasound were the most used and effective physical therapies for De Quervain tenosynovitis, but the primary treatment remains corticosteroid injections.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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