Differential Diagnosis for Delayed Walking, Waddling Gait, and Inability to Run in a Paediatric Patient
Single Most Likely Diagnosis
- Developmental Dysplasia of the Hip (DDH): This condition is a common cause of delayed walking and gait abnormalities in children. It occurs when the hip joint doesn't form properly, leading to instability and potential for dislocation, which can cause a waddling gait.
Other Likely Diagnoses
- Muscular Dystrophy (Duchenne or Becker): These genetic disorders lead to progressive muscle weakness, which can cause delayed walking, a waddling gait, and difficulty running due to the weakness of the proximal muscles.
- Cerebral Palsy: A group of disorders that affect movement and muscle tone, cerebral palsy can cause a variety of gait abnormalities, including a waddling gait, due to spasticity or weakness of the muscles.
- Congenital Neuromuscular Disorders: Conditions such as spinal muscular atrophy can lead to muscle weakness, affecting the child's ability to walk and run normally.
Do Not Miss Diagnoses
- Tumor or Space-Occupying Lesion (e.g., Brain or Spinal Tumor): Although less common, a tumor pressing on the spinal cord or brain can cause gait disturbances, including a waddling gait, due to compression of neural structures.
- Infectious or Inflammatory Conditions (e.g., Osteomyelitis, Discitis): Infections or inflammation of the bones or discs can cause pain and lead to abnormal gait as a way to minimize discomfort.
- Metabolic Bone Diseases (e.g., Rickets): Conditions that affect bone health can lead to softening of the bones, causing pain and gait abnormalities.
Rare Diagnoses
- Gaucher's Disease: A rare genetic disorder that can lead to bone and muscle abnormalities, potentially affecting gait.
- Mucopolysaccharidosis: A group of rare genetic disorders that can cause skeletal abnormalities, among other symptoms, potentially leading to gait issues.
- Friedreich's Ataxia: A rare genetic condition that affects the nervous system and can cause progressive damage to the spinal cord, leading to ataxia and gait disturbances.