From the Guidelines
Treatment for angular stomatitis should involve the application of antifungal creams like nystatin oral suspension 100,000 units four times daily for 1 week, or miconazole oral gel 5–10 mL held in the mouth after food four times daily for 1 week, as candidal infection is a common underlying cause 1. When treating angular stomatitis, it is essential to address both the symptoms and the underlying causes.
- Apply antifungal creams like nystatin oral suspension 100,000 units four times daily for 1 week, or miconazole oral gel 5–10 mL held in the mouth after food four times daily for 1 week, if a fungal infection is present 1.
- For bacterial infections, consider using an antiseptic oral rinse twice daily to reduce bacterial colonization of the mucosa, such as 1.5% hydrogen peroxide mouthwash or 0.2% chlorhexidine digluconate mouthwash 1.
- Topical corticosteroids, such as betamethasone sodium phosphate 0.5 mg in 10 mL water as a 3-min rinse-and-spit preparation, can be used to reduce inflammation and discomfort 1.
- Keep the area clean and dry, and avoid licking the corners of the mouth as saliva can worsen the condition.
- Apply petroleum jelly or zinc oxide as a protective barrier after treatment.
- If nutritional deficiencies are suspected, supplements of B vitamins, iron, or zinc may be recommended based on blood tests.
- For denture wearers, proper denture fit and hygiene are essential. It is crucial to note that most cases of angular stomatitis resolve within 2-3 weeks with proper treatment, but persistent or severe cases should be evaluated by a healthcare provider as they may indicate an underlying medical condition such as diabetes or immune dysfunction.
From the Research
Treatment for Angular Stomatitis
The treatment for angular stomatitis, also known as angular cheilitis, can vary depending on the underlying cause.
- In some cases, angular cheilitis is caused by a fungal infection, such as Candida albicans 2.
- Treatment for fungal-related angular cheilitis may include antifungal medications such as nystatin, clotrimazole, ketoconazole, and fluconazole 2.
- Other treatment options may include topical antiseptics and disinfectants, as well as good oral hygiene practices, such as regular cleaning and disinfection of dentures 3.
- In some cases, angular stomatitis may be related to nutritional deficiencies, such as vitamin B12 or folate deficiency 4, 5.
- Treatment for nutritional deficiency-related angular stomatitis may include supplementation with the deficient nutrient, as well as dietary changes to ensure adequate intake of essential vitamins and minerals 4, 5.
- New triazole antifungal agents, such as posaconazole and voriconazole, have also been shown to be effective against oral Candida isolates, including those that are resistant to other antifungal agents 6.