From the Guidelines
The recommended dosage for Loestrin (Ethinyl Estradiol and Norethindrone) is one tablet taken orally at the same time each day for 21 consecutive days, followed by 7 days of no medication or placebo tablets, depending on the specific formulation. Loestrin typically contains varying amounts of ethinyl estradiol (20-30 mcg) and norethindrone (1-1.5 mg) depending on the specific formulation (such as Loestrin 1/20, Loestrin 1.5/30, or Loestrin Fe) 1. The 28-day packs include 7 iron-containing placebo tablets to maintain the daily pill-taking routine. For maximum effectiveness, it's crucial to take the pill consistently without missing doses. If a dose is missed, follow the package instructions, which typically advise taking the missed pill as soon as remembered and the next pill at the regular time, even if it means taking two pills in one day 1. Additional contraception should be used for 7 days if pills are missed during the first week of the pack. Some key points to consider when prescribing Loestrin include:
- The patient should be counseled on the importance of taking the pill at the same time every day to maximize effectiveness
- A backup method of contraception, such as condoms, should be used for at least the first 7 days of taking the pill
- If more than one pill is missed in a row, the patient should take the most recently missed pill as soon as possible and continue with the regular schedule
- The patient should be informed of the potential risks and side effects of taking Loestrin, including the increased risk of blood clots and other serious health problems
- Regular follow-up appointments should be scheduled to monitor the patient's health and address any concerns or side effects. Loestrin works by suppressing ovulation, thickening cervical mucus to prevent sperm entry, and altering the endometrial lining to reduce the likelihood of implantation, providing effective contraception when taken correctly 1.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Loestrin Dosage
The recommended dosage for Loestrin, a combined oral contraceptive containing Ethinyl Estradiol and Norethindrone, is not explicitly stated in the provided studies. However, the following information can be gathered:
- The studies provided do not directly address the recommended dosage for Loestrin.
- Study 2 discusses the effects of different oral contraceptive regimens on hemoglobin, serum iron, and iron binding capacity in anemic women, but does not specify the dosage for Loestrin.
- Study 3 reviews the relationship between oral contraceptive use and iron status in women, but does not provide information on the recommended dosage for Loestrin.
- Study 4 examines the effect of prolonged use of intrauterine devices and oral contraceptives on iron nutrition, but does not specify the dosage for Loestrin.
- Study 5 discusses the use of oestrogens as a "morning-after pill," but does not provide information on the recommended dosage for Loestrin.
- Study 6 investigates the relationship between history of hormonal contraceptive use and iron status among women in Tanzania, but does not specify the dosage for Loestrin.
Key Points
- The studies provided do not directly address the recommended dosage for Loestrin.
- The dosage for Loestrin is not explicitly stated in the provided studies.
- Further research is needed to determine the recommended dosage for Loestrin.
Some possible dosages for combined oral contraceptives like Loestrin can be:
- 1 mg of ethinyloestradiol twice daily for 5 days, as mentioned in study 5.
- 5 mg of stilboestrol 5 times daily for 5 days, as mentioned in study 5.
- 25 mg elemental iron as ferrous fumarate, for seven days, per monthly tablet package, as mentioned in study 3.
However, these dosages may not be specific to Loestrin and should not be taken as recommendations. It is essential to consult the prescribing information or a healthcare professional for the correct dosage.