From the Research
Yes, Farxiga (dapagliflozin) can potentially increase the risk of dental infections. Farxiga belongs to a class of medications called SGLT2 inhibitors, which work by causing the kidneys to remove excess sugar from the body through urine. This medication can lead to increased glucose levels in saliva and may cause dry mouth, both of which create favorable conditions for bacterial growth in the oral cavity. While dental infections aren't among the most common side effects of Farxiga, patients taking this medication should be vigilant about oral hygiene. Regular brushing twice daily, daily flossing, adequate hydration, and routine dental check-ups are important preventive measures. If you notice symptoms such as gum pain, swelling, unusual tooth sensitivity, or persistent bad breath while taking Farxiga, contact your dentist promptly. The connection between SGLT2 inhibitors and oral health stems from their mechanism of action affecting glucose levels throughout the body, including in saliva, which can potentially alter the oral microbiome 1.
Key Considerations
- The mechanism of action of SGLT2 inhibitors like dapagliflozin can increase glucose levels in saliva, potentially leading to an increased risk of dental infections.
- Dry mouth, a possible side effect of dapagliflozin, can also contribute to the development of dental infections.
- Regular oral hygiene practices and dental check-ups are crucial for patients taking Farxiga to prevent dental infections.
- Although the provided studies do not directly address the risk of dental infections with dapagliflozin, the mechanism of action and potential side effects suggest a possible increased risk 2, 3, 4, 5, 1.
Recommendations for Patients Taking Farxiga
- Practice good oral hygiene, including regular brushing and flossing.
- Stay hydrated to help prevent dry mouth.
- Schedule routine dental check-ups to monitor oral health.
- Be aware of symptoms of dental infections, such as gum pain, swelling, or unusual tooth sensitivity, and contact a dentist promptly if they occur.