From the Guidelines
Glutathione therapy is not a recommended treatment for night sweats, as the current evidence does not support its effectiveness in addressing the underlying causes of this symptom. Night sweats are often caused by hormonal changes, infections, medications, or underlying health conditions, rather than oxidative stress that glutathione addresses 1. While glutathione is an important antioxidant in the body that helps combat oxidative stress and supports detoxification processes, it has not been established as a standard treatment for night sweats.
Key Considerations
- The provided evidence focuses on hormonal treatment of hot flashes, which may be related to night sweats but does not directly address glutathione therapy 1.
- Hormonal treatments, such as combination estrogen and progestins or estrogen alone, are effective for managing vasomotor symptoms like hot flashes in postmenopausal women, but their use in night sweats is not explicitly mentioned 1.
- Alternative approaches for managing night sweats, such as keeping the bedroom cool, using moisture-wicking bedding, avoiding alcohol and spicy foods before bed, and maintaining a healthy weight, may offer temporary relief.
Recommendation
For individuals experiencing night sweats, it is crucial to consult with a healthcare provider to determine the underlying cause and appropriate treatment. If night sweats are related to menopause, hormone therapy or certain medications might be prescribed. Glutathione supplements might support overall health but should not be relied upon as a primary treatment for night sweats. Always consult with a healthcare provider before starting any supplement regimen, especially if you have existing health conditions or take medications.
From the Research
Glutathione Therapy and Night Sweats
- There is no direct evidence to suggest that glutathione therapy can help with night sweats 2, 3, 4, 5.
- Night sweats are a nonspecific symptom that can be caused by various factors, including menopause, mood disorders, gastroesophageal reflux disease, hyperthyroidism, and obesity 2, 3, 4, 5.
- Glutathione has been studied in the context of menopausal women with insomnia, and it was found that glutathione levels and activity were altered in these women 6.
- However, there is no clear link between glutathione therapy and the treatment of night sweats, and more research is needed to determine its potential effectiveness 6.
Potential Causes of Night Sweats
- Menopause and hyperthyroidism are common hormonal causes of excessive sweating, including night sweats 5.
- Other potential causes of night sweats include panic attacks, sleeping disorders, hypogonadism, and certain medications 3, 4, 5.
- A thorough history, physical examination, and directed laboratory and radiographic studies are necessary to determine the underlying cause of night sweats 2, 3, 4.