Does Cannabidiol (CBD) oil increase anxiety?

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Last updated: June 20, 2025View editorial policy

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From the Research

Cannabidiol (CBD) oil generally does not increase anxiety; in fact, it may help reduce anxiety for many people. Research suggests that CBD has anxiolytic (anxiety-reducing) properties and works by interacting with serotonin receptors in the brain that regulate mood and social behavior 1. Typical doses for anxiety range from 300-600mg daily, though many commercial products contain lower amounts (25-75mg per serving). Some people may experience side effects like drowsiness, dry mouth, or digestive issues, and CBD can interact with certain medications that carry a grapefruit warning.

Key Findings

  • A 2023 study found that 300mg of oral CBD reduced anxiety symptoms across a 2-week administration period compared to placebo 1.
  • Another study published in 2020 found that acute doses of CBD were found to reduce anxiety both in animals and humans, without having an anxiogenic effect at higher doses 2.
  • A 2022 open-label trial also found that CBD can reduce anxiety severity and has an adequate safety profile in young people with treatment-resistant anxiety disorders 3.

Considerations

  • Individual responses vary, and a small percentage of users might experience increased anxiety, particularly at high doses.
  • CBD products are not well regulated, so quality and potency can be inconsistent.
  • Before trying CBD for anxiety, consult with a healthcare provider, especially if you take other medications or have existing health conditions.
  • Start with a low dose and gradually increase while monitoring your response.
  • It's also important to note that the current evidence is based on studies with small sample sizes, and more research is needed to confirm the efficacy and longer-term safety of CBD for anxiety disorders.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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