Trauma: This is the most common cause of pancreatitis in children, often resulting from blunt abdominal trauma, such as from a car accident or a fall. The force of the trauma can cause injury to the pancreas, leading to inflammation.

Viral infections: Certain viral infections, like mumps, coxsackievirus, and hepatitis, can cause pancreatitis in children. These infections can trigger an inflammatory response in the pancreas.
Gallstones: Although less common in children than in adults, gallstones can still cause pancreatitis by obstructing the pancreatic duct. This is more likely in older children and adolescents.
Medications: Some medications, such as valproic acid, can cause pancreatitis as a side effect. The likelihood depends on the specific medication and the child's individual response.
Genetic disorders: Conditions like cystic fibrosis can increase the risk of pancreatitis due to the abnormal production of pancreatic secretions.

Hypertriglyceridemia: Extremely high levels of triglycerides can cause pancreatitis. This condition is less common but critical to identify and treat promptly to prevent severe complications.
Autoimmune pancreatitis: A rare form of chronic pancreatitis characterized by an autoimmune response. Early recognition is crucial for appropriate management and to avoid unnecessary surgeries.
Pancreatic ductal anomalies: Congenital anomalies of the pancreatic duct, such as pancreas divisum, can increase the risk of pancreatitis. Identifying these anomalies is vital for guiding treatment.

Systemic lupus erythematosus (SLE): SLE can cause pancreatitis as part of its multi-system involvement, though this is rare in children.
Inflammatory bowel disease (IBD): Conditions like Crohn's disease and ulcerative colitis can rarely cause pancreatitis, possibly due to shared inflammatory pathways or medication side effects.
Tumors: Pancreatic tumors, whether benign or malignant, are rare in children but can cause pancreatitis by obstructing the pancreatic duct or through other mechanisms.