From the FDA Drug Label
Storage Protect from light. Store unopened bottle(s) under refrigeration at 2° to 8°C (36° to 46°F). During shipment to the patient, the bottle may be maintained at temperatures up to 40°C (104°F) for a period not exceeding 8 days. Once a bottle is opened for use, it may be stored at room temperature up to 25°C (77°F) for 6 weeks.
- Unopened Latanoprost eye drops need to be refrigerated at 2° to 8°C (36° to 46°F) 1.
- Opened bottles can be stored at room temperature up to 25°C (77°F) for 6 weeks 1.
From the Research
Latanoprost eye drops do not necessarily need to be refrigerated after opening, as they can be stored at room temperature for up to 6 weeks. When you first purchase Latanoprost, it is recommended to keep the unopened bottle in the refrigerator at 36-46°F (2-8°C) to maintain the stability of the medication, as Latanoprost is sensitive to heat and light 2. However, after opening the bottle, you can keep it at room temperature, but should use it within 6 weeks to ensure effectiveness, as studies have shown that latanoprost remains stable and effective when stored at room temperature for up to 6 weeks after opening 3, 2. The drug works by increasing the outflow of aqueous humor from the eye, which reduces intraocular pressure. To properly use Latanoprost, apply one drop in the affected eye(s) once daily, preferably in the evening. Always wash your hands before administration, avoid touching the dropper tip to prevent contamination, and close the bottle tightly after each use. If you're using multiple eye medications, wait at least 5 minutes between applications. It's worth noting that more recent studies have focused on improving the bioavailability and stability of latanoprost, such as the development of latanoprost-loaded cyclodextrin microaggregate suspension eye drops 4, but the basic storage and handling instructions remain the same. Overall, the key is to use the medication within the recommended timeframe and follow proper handling and storage procedures to ensure its effectiveness and safety.