What initial lab tests should be ordered for a 39-year-old female with bleeding hemorrhoids, a history of hemorrhoidectomy (surgical removal of hemorrhoids), and symptoms of pain and pressure?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: June 20, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

For a 39-year-old female with bleeding hemorrhoids, history of hemorrhoidectomy, and symptoms of pain and pressure, I recommend ordering a complete blood count (CBC), determination of hemoglobin and hematocrit, and assessment of coagulation as initial laboratory tests. The CBC will assess for anemia from chronic blood loss, with particular attention to hemoglobin, hematocrit, and red blood cell indices. Determining hemoglobin and hematocrit will help evaluate the severity of the bleeding 1. Assessing coagulation, including prothrombin time (PT), partial thromboplastin time (PTT), and international normalized ratio (INR), would help rule out bleeding disorders that could exacerbate hemorrhoidal bleeding.

  • These tests are important because recurrent hemorrhoidal bleeding can lead to significant anemia requiring iron supplementation or even transfusion in severe cases.
  • The history of previous hemorrhoidectomy raises concern for recurrence or incomplete treatment, making it essential to quantify blood loss and establish baseline values before considering further interventions.
  • If bleeding is significant or persistent, additional tests like colonoscopy might be warranted to rule out other colorectal pathologies that could present with similar symptoms, as suggested by the American Gastroenterological Association technical review on the diagnosis and treatment of hemorrhoids 1.
  • In case of severe bleeding, blood typing and cross-matching should also be considered, as suggested by the WSES-AAST guidelines 1.

From the Research

Initial Lab Tests for Bleeding Hemorrhoids

To evaluate a 39-year-old female with bleeding hemorrhoids, a history of hemorrhoidectomy, and symptoms of pain and pressure, the following lab tests should be considered:

  • Complete Blood Count (CBC) to assess for anemia, as hemorrhoidal bleeding can lead to significant blood loss 2
  • Coagulation studies, such as prothrombin time (PT) and partial thromboplastin time (PTT), to evaluate for any coagulopathy that may be contributing to the bleeding 3
  • Electrolyte panel to assess for any electrolyte imbalances that may be contributing to the patient's symptoms
  • Blood type and screen, in case blood transfusion is required due to significant blood loss 4

Rationale for Lab Tests

The patient's history of hemorrhoidectomy and current symptoms of bleeding and pain suggest the possibility of significant blood loss and potential anemia. The lab tests listed above can help to evaluate the severity of the blood loss and identify any underlying coagulopathy or electrolyte imbalances that may be contributing to the patient's symptoms.

Additional Considerations

The patient's age and symptoms are consistent with the typical presentation of hemorrhoids, as described in the literature 5. However, the presence of significant bleeding and pain warrants further evaluation to rule out other potential causes of these symptoms. The patient's history of hemorrhoidectomy also suggests the possibility of recurrent disease, which should be considered in the evaluation and management of her current symptoms.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Evaluation of anemia caused by hemorrhoidal bleeding.

Diseases of the colon and rectum, 1994

Research

Hemorrhoidectomy: indications and risks.

European journal of medical research, 2004

Research

Preoperative Blood Transfusion Requirements for Hemorrhoidal Severe Anemia: A Retrospective Study of 128 Patients.

Medical science monitor : international medical journal of experimental and clinical research, 2024

Research

Hemorrhoids: Diagnosis and Treatment Options.

American family physician, 2018

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.