What causes a large bullous blister on the foot after playing soccer?

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Last updated: June 20, 2025View editorial policy

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From the Research

A large bullous blister on the foot after playing soccer is typically caused by repetitive shear deformation, which is a result of the motion of bone, high friction force, and repetition of the resulting shear events, as explained in the study by 1. This occurs when the skin is subjected to repeated stress and friction, leading to a separation between layers of skin, with fluid filling the space to protect the underlying tissue. The most common locations are the heel, toes, or ball of the foot where pressure and movement are greatest during soccer. Contributing factors include ill-fitting shoes, excessive moisture from sweat, improper socks, or playing on rough surfaces. Some key points to consider when treating and preventing blisters include:

  • Wearing properly fitted soccer cleats with moisture-wicking socks to reduce friction and moisture
  • Applying petroleum jelly to high-friction areas to reduce friction
  • Using foot powder to reduce moisture
  • Gradually breaking in new footwear to prevent excessive stress on the skin
  • Avoiding popping the blister if possible, as the fluid provides protection, but draining it if it's large and painful, and covering with an antibiotic ointment and sterile bandage
  • Keeping the area clean and protected with moleskin or a blister pad
  • Seeking medical attention promptly if the blister shows signs of infection, such as increasing pain, redness, warmth, pus, or red streaks, as highlighted in the study by 2. It's also important to note that the traditional blister causation paradigm revolving around heat, moisture, and friction is being challenged by new research, such as the study by 1, which highlights the importance of repetitive shear deformation in the development of friction blisters. Additionally, the study by 3 emphasizes the need for more effective prevention strategies, and the study by 4 provides guidance on the treatment and prevention of friction blisters. However, the most recent and highest quality study, 1, provides the most relevant information for treating and preventing large bullous blisters on the foot after playing soccer.

References

Research

Friction blisters. Pathophysiology, prevention and treatment.

Sports medicine (Auckland, N.Z.), 1995

Research

Friction Blisters.

The Physician and sportsmedicine, 1982

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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