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Last updated: June 23, 2025View editorial policy

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Differential Diagnosis for Easy Bruising

  • Single most likely diagnosis
    • Vitamin C deficiency (Scurvy): Easy bruising is a common symptom of scurvy due to the role of vitamin C in collagen synthesis and blood vessel integrity. This condition is relatively common, especially in individuals with poor dietary habits or increased requirements.
  • Other Likely diagnoses
    • Vitamin K deficiency: Vitamin K is essential for the production of clotting factors in the liver. A deficiency can lead to easy bruising due to impaired blood clotting.
    • Platelet disorders (e.g., thrombocytopenia or platelet dysfunction): Conditions affecting platelet count or function can lead to easy bruising due to the body's reduced ability to form blood clots.
    • Medication side effects (e.g., anticoagulants, steroids): Certain medications, such as anticoagulants and steroids, can increase the risk of easy bruising as a side effect.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Leukemia: Leukemia can cause easy bruising due to bone marrow suppression leading to thrombocytopenia or platelet dysfunction. Early detection is crucial for effective treatment.
    • Liver disease (e.g., cirrhosis): Liver disease can lead to coagulopathy due to decreased production of clotting factors, resulting in easy bruising. Liver disease can have severe consequences if not addressed.
    • Bleeding disorders (e.g., hemophilia): Although less common, bleeding disorders like hemophilia can present with easy bruising and require prompt diagnosis to prevent severe complications.
  • Rare diagnoses
    • Ehlers-Danlos syndrome: A group of genetic disorders affecting connective tissue, which can lead to easy bruising due to fragile blood vessels.
    • Pseudoxanthoma elasticum: A rare genetic disorder affecting elastic fibers in connective tissue, leading to easy bruising among other symptoms.
    • Amyloidosis: A condition characterized by the deposition of amyloid proteins in various tissues, which can lead to easy bruising due to blood vessel fragility.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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