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Differential Diagnosis for a 62-year-old Female Patient with Abdominal Symptoms and Pelvic Mass

Single Most Likely Diagnosis

  • Ovarian Cancer: This is the most likely diagnosis given the patient's symptoms of abdominal bloating, early satiety, increased abdominal girth, and imaging evidence of a pelvic mass with peritoneal spread. Ovarian cancer is known for its non-specific symptoms until late stages and often presents with spread to the peritoneum.

Other Likely Diagnoses

  • Uterine Cancer: Although less common than ovarian cancer with these specific symptoms, uterine cancer can also present with a pelvic mass and spread to the peritoneum, especially in postmenopausal women.
  • Gastrointestinal Cancer (e.g., Gastric or Colorectal Cancer): These cancers can metastasize to the peritoneum and cause similar symptoms, including abdominal bloating and early satiety, though they are less likely to present as a primary pelvic mass.

Do Not Miss Diagnoses

  • Lymphoma: Although less common, lymphoma can present with abdominal symptoms and a mass, and it is crucial not to miss this diagnosis due to its different treatment approach and potential for cure with early detection.
  • Tuberculous Peritonitis: This condition can mimic peritoneal carcinomatosis and is important to consider, especially in endemic areas or in patients with risk factors for tuberculosis, as it requires a different treatment approach.

Rare Diagnoses

  • Primary Peritoneal Cancer: This is a rare cancer that arises from the peritoneum itself and can present similarly to ovarian cancer, with abdominal bloating, ascites, and a pelvic mass.
  • Pseudomyxoma Peritonei: A rare clinical syndrome characterized by recurrent mucinous ascites causing abdominal distension, often associated with a primary mucinous tumor of the appendix.
  • Mesothelioma: A rare cancer of the peritoneum that can cause similar symptoms, including abdominal bloating and a mass, though it is more commonly associated with asbestos exposure.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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