Can eye drops be used to treat hordeolum (stye)?

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Last updated: June 23, 2025View editorial policy

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From the Research

Eye drops can be used to treat a hordeolum (stye), but they're not the primary treatment, and their effectiveness is supported by the most recent study from 2023 1.

Treatment Overview

The mainstay of treatment for hordeolum (stye) includes warm compresses applied to the affected eyelid for 10-15 minutes, 3-4 times daily, which helps bring the stye to a head and promote drainage.

  • Over-the-counter pain relievers like ibuprofen or acetaminophen can help with discomfort.
  • It's essential to avoid wearing contact lenses and eye makeup during treatment.
  • Most styes resolve within a week with these measures.

Role of Eye Drops

Antibiotic eye drops such as azithromycin hydrate ophthalmic solution may be prescribed if the stye is infected or not responding to home treatment, as shown in a study from 2023 1.

  • These are typically applied twice daily for 2 days and then once daily for 12 days.
  • Eye drops work by controlling bacterial infection and reducing inflammation in and around the oil glands of the eyelid.
  • However, the addition of an antibiotic to conservative measures for a hordeolum was not associated with an increased likelihood of treatment success, as noted in a study from 2022 2.

Important Considerations

If a stye doesn't improve within a week, becomes increasingly painful, affects vision, or recurs frequently, medical attention should be sought as incision and drainage might be necessary.

  • It's also crucial to be aware of potential systemic side effects of ophthalmic drops, as discussed in a case report from 2022 3.
  • Providers must educate patients on common systemic side effects of such drugs when prescribing topical ophthalmologic drops.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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