What does it mean if I have different blood pressure readings in each arm?

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Last updated: June 23, 2025View editorial policy

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From the Guidelines

Having different blood pressure readings in each arm is a significant finding that requires attention, especially if the difference is 10 mmHg or more, as it may indicate underlying health issues such as peripheral artery disease or atherosclerosis. This difference occurs because blood vessels supplying one arm may be narrowed or blocked, reducing blood flow and pressure in that arm. According to the 2020 international society of hypertension global hypertension practice guidelines 1, initial evaluation should include measuring blood pressure in both arms, preferably simultaneously, and if there is a consistent difference between arms >10 mm Hg in repeated measurements, the arm with the higher BP should be used.

Key Points to Consider

  • A consistent difference of 10-15 mmHg or more between arms could indicate underlying health issues such as peripheral artery disease, atherosclerosis, aortic dissection, or other cardiovascular problems.
  • If you notice a significant difference between arms, you should consult your healthcare provider for evaluation, especially if you have risk factors for heart disease or experience symptoms like chest pain or shortness of breath.
  • During diagnosis, your doctor will likely measure your blood pressure in both arms and may order additional tests like ultrasound or angiography if needed.
  • For ongoing blood pressure monitoring at home, use the arm with the higher reading for consistency, as this more accurately reflects your cardiovascular status, as recommended by the 2020 international society of hypertension global hypertension practice guidelines 1.

Importance of Accurate Blood Pressure Measurement

Accurate blood pressure measurement is crucial for diagnosing and managing hypertension. The use of validated automated upper arm cuff devices with appropriate cuff size for the individual patient is recommended, as stated in the 2020 international society of hypertension global hypertension practice guidelines 1. Additionally, the guidelines recommend measuring blood pressure in both arms at the first visit and using the arm with the higher reading for consistency.

Next Steps

If you have different blood pressure readings in each arm, it is essential to consult your healthcare provider for evaluation and guidance. They will assess your overall cardiovascular health and determine the best course of action. In some cases, further testing may be necessary to rule out underlying conditions. By prioritizing your cardiovascular health and seeking medical attention if you notice a significant difference in blood pressure readings between arms, you can reduce your risk of morbidity, mortality, and improve your quality of life.

From the Research

Inter-Arm Blood Pressure Differences

Having different blood pressure readings in each arm can be a significant finding. Research studies have investigated the prevalence and implications of inter-arm blood pressure differences.

  • A study published in the Journal of Hypertension in 2002 found that significant differences in blood pressure between the two arms were present in 20% of participants for systolic blood pressure and 11% for diastolic blood pressure 2.
  • Another study published in The American Journal of Emergency Medicine in 2001 found that 15% of normotensive individuals had differences in systolic blood pressure between both arms exceeding 10 mmHg 3.
  • A study published in the Korean Journal of Family Medicine in 2013 found that the mean absolute inter-arm difference in systolic blood pressure was 3.19 ± 2.38 mmHg in men and 2.61 ± 2.18 mmHg in women, with most patients having an inter-arm difference of ≤ 10 mmHg 4.
  • A study published in Anaesthesia in 2013 found that the prevalence of a systolic inter-arm difference ≥ 15 mmHg was 26% in vascular surgical patients, which could lead to monitoring errors 5.

Clinical Implications

Inter-arm blood pressure differences can have significant clinical implications, including:

  • Delayed diagnosis of hypertension 6
  • Poorer control of blood pressure levels 6
  • Association with other signs of vascular disease, such as peripheral arterial disease or cerebrovascular disease 6
  • Increased cardiovascular mortality and morbidity, and all-cause mortality 6

Measurement and Detection

It is essential to measure blood pressure in both arms initially to prevent misdiagnosis of hypertension due to normal differences in blood pressure between the arms 2. The method of measurement used can affect the prevalence of inter-arm differences, and current best practice for detection and measurement should be followed 6.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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