Is it safe to take biotin (Vitamin B7) with hypothyroidism?

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Last updated: June 23, 2025View editorial policy

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From the Research

It is generally safe to take biotin with hypothyroidism, but caution is advised due to potential interference with thyroid function tests, particularly at high doses. When considering taking biotin supplements, it's essential to be aware of the potential effects on laboratory tests used to monitor thyroid function. Biotin supplements can interfere with these tests, potentially causing falsely high or low results that might lead to improper treatment adjustments 1, 2, 3, 4. However, a recent study found that low-dose biotin supplements (<300μg/day) have minimal clinical relevance and do not typically require adjustments to thyroxine replacement doses in patients with hypothyroidism 5.

Some key points to consider:

  • Biotin itself does not typically worsen hypothyroidism; the main concern is its effect on test accuracy and potential medication interactions.
  • High doses of biotin (1,000-10,000 micrograms) are more likely to cause test interference than low doses (<300μg/day).
  • If you take biotin supplements, it's recommended to stop taking them at least 2-3 days before any thyroid blood tests to minimize potential interference.
  • Discussing biotin supplementation with your healthcare provider is crucial, especially if you're on thyroid medication or getting thyroid tests, to determine the best course of action and prevent any potential issues 5.

In terms of morbidity, mortality, and quality of life, the most critical consideration is ensuring accurate thyroid function test results to guide treatment decisions. By being aware of the potential effects of biotin supplements on these tests and taking steps to minimize interference, individuals with hypothyroidism can help ensure optimal management of their condition.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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