What causes orange skin?

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Last updated: June 23, 2025View editorial policy

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From the Research

Orange skin is primarily caused by excessive consumption of carotenoid-rich foods, a condition called carotenemia, as evidenced by a recent study published in 2022 1. This condition occurs when beta-carotene accumulates in the bloodstream and deposits in the skin, particularly in areas with thicker skin like palms, soles, and nasolabial folds. Some key points to consider:

  • Unlike jaundice, the whites of the eyes remain normal in carotenemia.
  • Other causes include certain medications such as quinacrine, medical conditions like hypothyroidism which slows carotenoid metabolism, and some liver diseases.
  • Artificial tanning products containing dihydroxyacetone (DHA) can also create an orange appearance if applied incorrectly.
  • For food-related carotenemia, reducing intake of carotenoid-rich foods typically resolves the condition within weeks to months, as the body gradually eliminates the excess carotenoids.
  • The condition is generally harmless, though persistent unexplained skin discoloration should be evaluated by a healthcare provider to rule out more serious causes, as noted in a case report from 2019 2.
  • It's worth noting that carotenemia can be caused by the excessive intake of various carotenoid-rich foods, including carrots, sweet potatoes, pumpkins, and other yellow or orange-colored foods, as well as some green vegetables, as reported in earlier studies 3, 4, 5.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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