From the Guidelines
The recommended dose of Nasonex (mometasone furoate) is 2 sprays per nostril every day for adults and children 12 years and older, and 1 spray per nostril every day for children 2-11 years old. According to the clinical practice guideline on allergic rhinitis 1, the dosing for Nasonex is as follows:
- Age 2-11 years: 1 spray per nostril every day
- Age 12 years and older: 2 sprays per nostril every day
- Age 18 years and older with nasal polyps: 2 sprays per nostril twice a day It is essential to use Nasonex regularly as prescribed, even when symptoms improve, to maintain control of nasal symptoms. The medication works by reducing inflammation in the nasal passages, which helps relieve symptoms of allergic rhinitis such as sneezing, itching, runny nose, and congestion. Most patients begin to feel relief within a short period of use, though full therapeutic effect may take up to several weeks of regular use. Some key points to consider when using Nasonex include:
- Priming the bottle before first use by pumping 10 times until a fine mist appears
- Repriming the spray with 2 sprays if it hasn't been used for more than a week
- Shaking the bottle gently before each use
- Clearing your nasal passages of mucus before spraying By following the recommended dose and usage guidelines, patients can effectively manage their allergic rhinitis symptoms and improve their quality of life.
From the FDA Drug Label
Use one spray in each nostril once daily. Users age 12 or older Use two sprays in each nostril every day. The recommended dose of Nasonex (mometasone furoate) is:
- For children age 2 to 11: one spray in each nostril once daily.
- For users age 12 or older: two sprays in each nostril every day 2.
From the Research
Nasonex Dose Information
The recommended dose of Nasonex (mometasone furoate) varies depending on the patient's age and the condition being treated.
- For adults and children over 12 years of age, the recommended dose is 200 micrograms once daily 3, 4, 5.
- For children between 6 and 11 years of age, the recommended dose is 100 micrograms once daily 6.
- For children between 2 and 5 years of age, there is no specific dose recommendation provided in the available studies.
Dose Efficacy and Tolerability
Studies have shown that mometasone furoate is effective in reducing nasal symptoms in patients with seasonal and perennial allergic rhinitis 6, 4, 5.
- A dose-ranging study in children with seasonal allergic rhinitis found that 100 micrograms once daily was the most effective dose, with no significant additional benefit from a 200 microgram dose 6.
- A study in adults with perennial rhinitis found that 200 micrograms once daily was effective in reducing nasal symptoms, with no evidence of tachyphylaxis 4.
- A dose-ranging study in adults with seasonal allergic rhinitis found that 200 micrograms once daily was the optimum dose, with all doses showing activity in reducing nasal symptoms 5.
Comparison with Other Treatments
Mometasone furoate has been compared to other intranasal corticosteroids, such as fluticasone propionate, and has been found to be at least as effective 4.
- A study comparing mometasone furoate to fluticasone propionate in patients with perennial rhinitis found that both treatments were effective in reducing nasal symptoms, with no significant difference between the two 4.