What is the recommended Human Papillomavirus (HPV) vaccine dosing schedule for a 36-year-old?

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Last updated: June 23, 2025View editorial policy

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From the Guidelines

For a 36-year-old, the recommended Human Papillomavirus (HPV) vaccine dosing schedule is a 3-dose series. The schedule consists of the first dose, followed by a second dose 1-2 months later, and a third dose 6 months after the first dose, as per the FDA approval of Gardasil 9 for men and women aged 26 to 45 years 1. While HPV vaccination is routinely recommended for adolescents at ages 11-12, adults through age 45 can still benefit from vaccination based on shared clinical decision-making with their healthcare provider. Some key points to consider:

  • The vaccine is most effective when given before exposure to HPV through sexual activity, but even sexually active adults may benefit from protection against HPV types they haven't yet encountered.
  • The vaccine helps prevent HPV infections that can lead to certain cancers and genital warts.
  • Insurance coverage for adults over 26 varies, so checking with your insurance provider about coverage is advisable before starting the vaccination series. It's essential to note that the Advisory Committee on Immunization Practices is expected to consider updated recommendations for individuals in this age group, but as of now, the 3-dose series is the recommended schedule 1.

From the Research

HPV Vaccine Dosing Schedule

The recommended Human Papillomavirus (HPV) vaccine dosing schedule varies based on the age of initiation and other factors.

  • For individuals who initiate the vaccination series at ages 9 through 14 years, a 2-dose schedule is recommended, with doses spaced 6 to 12 months apart 2, 3.
  • For individuals who initiate the vaccination series at ages 15 through 26 years, a 3-dose schedule is recommended 2.
  • There is also evidence to suggest that even one-dose vaccination may be sufficient to provide prolonged protection against HPV infection and associated diseases, although this is still being studied 4.

Considerations for a 36-Year-Old

  • The studies provided do not specifically address the recommended dosing schedule for a 36-year-old.
  • However, it can be inferred that a 3-dose schedule may be recommended for individuals aged 26 and older, as the 2-dose schedule is typically recommended for those who initiate vaccination at a younger age 2, 3.
  • It is essential to consult with a healthcare professional to determine the best course of action for an individual's specific situation.

Additional Information

  • The HPV vaccine has been shown to be highly effective in preventing HPV-related diseases, including cervical cancer and genital warts 5, 3.
  • The 9-valent HPV vaccine provides protection against 7 high-risk types of HPV responsible for 90% of cervical cancers and 2 other HPV types accounting for 90% of genital warts 3.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

From the monovalent to the nine-valent HPV vaccine.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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